Tumor development relies on the interactions of malignant cells with different non-malignant components within tumor microenvironment.
The research focus of my lab is to understand the role of tumor-neuro-immune axis in promoting melanoma and non-melanoma skin cancer development and progession. 
Furthermore, we are developing therapies which target emerging new players within tumor microenvironment. Specific projects include:
- Understand how melanoma interaction with sensory neurons and Schwann cells promotes tumor progression.
- Characterize how Schwann cells within tumor microenvironment promote immune-suppression.
- Develop new technology for single cell isolation and characterization from skin biopsies.
- Develop new topical immunotherapy to treat high-risk melanoma and non-melanoma skin cancer.
Dr. Bunimovich's publications can be reviewed here.